This Handbook of COVID-19 Prevention and Treatment was compiled according to clinical experience at The First Affliated Hospital, Zhejiang University School of Medicine
Faced with an unknown virus, sharing and collaboration are the best remedy.
The publication of this Handbook is one of the best ways to mark the courage and wisdom our healthcare workers have demonstrated over the past two months.
Thanks to all those who have contributed to this Handbook, sharing the invaluable experience with healthcare colleagues around the world while saving the lives of patients.
Thanks to the support from healthcare colleagues in China who have provided experience that inspires and motivates us.
Thanks to Jack Ma Foundation for initiating this program, and to AliHealth for the technical support, making this Handbook possible to support the fight against the epidemic.
The Handbook is available to everyone for free. However, due to the limited time, there might be some errors and defects. Your feedback and advice are highly welcomed!
Prof. Tingbo LIANG Editor-in-Chief of the Handbook of COVID-19 Prevention and Treatment Chairman of The First Aﬃliated Hospital, Zhejiang University School of Medicine
This is an unprecedented global war, and mankind is facing the same enemy, the novel corona-virus. And the first battlefield is the hospital where our soldiers are the medical workers.
To ensure that this war can be won, we must first make sure that our medical staﬀ is guaranteed suﬃcient resources, including experience and technologies. Also, we need to make sure that the hospital is the battleground where we eliminate the virus, not where the virus defeats us.
Therefore, the Jack Ma Foundation and Alibaba Foundation have convened a group of medical experts who have just returned from the frontlines of fighting the pandemic. With the support of The First Aﬃliated Hospital, Zhejiang University School of Medicine (FAHZU), they quickly published a guidebook on the clinical experience of how to treat this new coronavirus. The treatment guide oﬀers advice and reference against the pandemic for medical staﬀ around the world who are about to join the war.
My special thanks goes out to the medical staﬀ from FAHZU. While taking huge risks in treating COVID-19 patients, they recorded their daily experience which is reflected in this Handbook. Over the past 50 days, 104 confirmed patients have been admitted to FAHZU, including 78 severe and critically ill ones. Thanks to the pioneering eﬀorts of medical staﬀ and the application of new technologies, to date, we have witnessed a miracle. No staﬀ were infected, and there were no missed diagnosis or patient deaths.
Today, with the spread of the pandemic, these experiences are the most valuable sources of information and the most important weapon for medical workers on the frontline. This is a brand-new disease, and China was the first to suﬀer from the pandemic. Isolation, diagnosis, treatment, protective measures, and rehabilitation have all started from scratch. WE hope that this Handbook can provide doctors and nurses in other aﬀected areas valuable information so they don’t have to enter the battlefield alone.
This pandemic is a common challenge faced by mankind in the age of globalization. At this moment, sharing resources, experiences and lessons, regardless of who you are, is our only chance to win. The real remedy for this pandemic is not isolation, but cooperation.
This war has just begun.
Part One Prevention and Control Management
I. Isolation Area Management 1
II. Staﬀ Management 4
III. COVID-19 Related Personal Protection Management 5
IV. Hospital Practice Protocols during COVID-19 Epidemic 6
V. Digital Support for Epidemic Prevention and Control 16
Part Two Diagnosis and Treatment
I. Personalized, Collaborative and Multidisciplinary Management 18
II.Etiology and Inflammation Indicators 19
III. Imaging Findings of COVID-19 Patients 21
IV. Application of Bronchoscopy in the Diagnosis and Management of COVID-19 Patients 22
V. Diagnosis and Clinical Classification of COVID-19 22
VI. Antiviral Treatment for Timely Elimination of Pathogens 23
VII. Anti-shock and Anti-hypoxemia Treatment 24
VIII. The Rational Use of Antibiotics to Prevent Secondary Infection 29
IX. The Balance of Intestinal Microecology and Nutritional Support 30
X. ECMO Support for COVID-19 Patients 32
XI. Convalescent Plasma Therapy for COVID-19 Patients 35
XII. TCM Classification Therapy to Improve Curative Eﬃcacy 36
XIII. Drug Use Management of COVID-19 Patients 37
XIV. Psychological Intervention for COVID-19 Patients 41
XV. Rehabilitation Therapy for COVID-19 Patients 42
XVI. Lung Transplantation in Patients with COVID-19 44
XVII. Discharge Standards and Follow-up Plan for COVID-19 Patients 45
Part Three Nursing
I. Nursing Care for Patients Receiving High-Flow Nasal Cannula (HFNC) Oxygen Therapy 47
II. Nursing Care in Patients with Mechanical Ventilation 47
III. Daily Management and Monitoring of ECMO (Extra Corporeal Membrane Oxygenation) 49
IV. Nursing Care of ALSS (Artificial Liver Support System) 50
V. Continuous Renal Replacement Treatment (CRRT) Care 51
VI. General Care 52
I. Medical Advice Example for COVID-19 Patients 53
II. Online Consultation Process for Diagosis and Treatment 57